Learn more about ISENTRESS, a prescription HIV-1 medicine. See important risk info. Drug information on Raltegravir Tablet (chewable), tablet (film coated), granule for oral suspension for health care professionals. Drug information on Raltegravir for patients and consumers. side effects of raltegravir, read the drug label or package insert or talk to your health care provider.
|Published (Last):||10 June 2006|
|PDF File Size:||20.66 Mb|
|ePub File Size:||6.35 Mb|
|Price:||Free* [*Free Regsitration Required]|
View explanations for tiers and restrictions. Most commonly, these are “non-preferred” brand drugs or specialty prescription products. Step Therapy Drugs that have raltegravir package insert therapy associated with each prescription.
Severe, potentially life-threatening and fatal skin reactions reported; skin reactions raltegravir package insert cases raltegravir package insert Stevens-Johnson syndrome, raltegrvair reaction and toxic epidermal necrolysis; immediately discontinue treatment if severe hypersensitivity, severe rash, or rash with systemic symptoms or liver aminotransferase elevations develops and monitor clinical status, including liver aminotransferases closely.
Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
What would you like to print?
Positive evidence of human fetal risk. Raltegravir package insert tablets contain phenylalanine, a component of aspartame Drug interactions overview Coadministration of raltegravir package insert with drugs that inhibit UGT1A1 eg, rifampin may reduce plasma levels of raltegravir see Dosage Modifications Coadministration with other strong inducers eg, carbamazepine, phenobarbital, phenytoin of drug metabolizing enzymes on raltegravir is unknown and therefore not recommended.
Print with Office Info. This website also contains material copyrighted by 3rd parties.
Isentress, Isentress HD (raltegravir) dosing, indications, interactions, adverse effects, and more
Create Your List of Plans. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data raltegravir package insert from primary medical literature.
Share cases and questions with Physicians on Medscape consult. Coadministration with drugs that raltwgravir strong inducers of UGT1A1 may result in reduced plasma concentrations of raltegravir. Risks involved outweigh raltegravir package insert benefits.
Unknown if drug is removed by dialysis; avoid dosing before dialysis session. Owing to the potential for HIV transmission in HIV-negative infantsdeveloping viral resistance in HIV- positive infantsraltegravir package insert adverse reactions in a breastfed infant, instruct mothers not to breastfeed if they are receiving therapy. The use of other active agents with raltegravir is associated with a greater likelihood of treatment response.
Available data from APR raltegravir package insert no difference in rate of overall birth defects for raltegravir compared to background rate for major birth defects of 2.
This drug is available at a higher level co-pay. If you log out, you will be required to enter your username and password the next time you raltegravir package insert. Tier Raltegravir package insert 1 This drug is available at the lowest co-pay.
ST Step Therapy Drugs that have step therapy associated with each prescription. May be chewed or swallowed whole. Dosing Considerations Combination regimen is based on safety, tolerability, pharmacokinetic parameters, and efficacy data through at least wk in a multicenter, open-label, noncomparative study in HIV-1 infected children and adolescents aged 4 wk to insfrt yr Do not substitute chewable tablets or oral suspension for film-coated tablets; these are not bioequivalent, and therefore, are not interchangeable Do not switch between film-coated mg and mg tablet if prescribed dose is mg.
Raltegravir package insert Quantity Limits Drugs that have quantity limits associated with each prescription. Do not use in pregnancy. By clicking send, you acknowledge packabe you inserh permission pwckage email the recipient with this information.
Postmarketing Reports Blood and lymphatic raltegravig disorders: In animal reproduction studies in rats and rabbits, no evidence of adverse developmental outcomes observed with raltegravir package insert administration during organogenesis at doses that produced exposures up to approximately 4 times maximal packzge human dose MRHD of mg.
Must be swallowed whole Chewable tablet: Do not substitute chewable tablets or oral suspension for film-coated tablets; these are not bioequivalent, and therefore, are not interchangeable. Share Email Print Feedback Close. Combination regimen is based on safety, tolerability, pharmacokinetic parameters, and efficacy raltegravir package insert through at least wk in a multicenter, open-label, noncomparative study in HIV-1 infected children and adolescents aged 4 wk to 18 yr.
Most commonly, these ralteegravir “non-preferred” brand drugs. There is a pregnancy exposure registry that monitors pregnancy outcomes in women; healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry APR at 1- OR Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Print without Office Info. Contact the applicable plan provider for the most current information. Adding plans allows you to compare formulary status to other drugs in raltegravlr same class.
Prior Authorization Drugs that require prior authorization. Controlled studies in pregnant women show no evidence of fetal risk.
Formulary Formulary Patient Discounts. The above information is provided for general informational and educational purposes only. Your list will be saved and can be edited at any time. Absorption Fasted state Peak plasma concentration: Not studied Isentress HD Safety and efficacy not established; administration is not recommended. Isentress, Isentress HD Classes: Effect of food Low fat AUC ratio: Print this section Print the entire contents of. No data are available on presence of raltegravir in human milk, effects on breastfed infant, or on milk production; when administered to lactating rats, raltegravir was present in milk.
Rhabdomyolysis Nervous raltegravir package insert disorders: Need a Curbside Consult? Lactation The Centers for Disease Control and Prevention recommend that Raltegravir package insert infected raltegravir package insert in United States not breastfeed infants to avoid risking postnatal transmission of HIV-1 infection No data are available on presence of raltegravir in human milk, effects on breastfed infant, or on milk production; when administered to lactating rats, raltegravir was present in milk Owing to the potential for HIV transmission in HIV-negative infantsdeveloping viral resistance in HIV- positive infantsand adverse raltegravir package insert in a breastfed infant, instruct mothers not to breastfeed if they are receiving raltegravir package insert.
Renal impairment No dosage adjustment required for any degree of renal impairment Dialysis: